abstract：AIMS:Diffuse large B-cell lymphomas (DLBCL) can be divided into different subgroups (germinal center B-cell-like [GCB] and non-GCB) according to their gene expression profiles. Immunohistochemistry has been proposed as a surrogate for identifying these subgroups, but data about its efficacy in providing prognostic info...

journal_title：International journal of surgical pathology

authors： Laszlo D,Pruneri G,Andreola G,Radice D,Calabrese L,Rafaniello PR,Nassi L,Sammassimo S,Alietti A,Agazzi A,Vanazzi A,Martinelli G

更新日期：2011-08-01 00:00:00

abstract：:Spontaneous regression of malignant tumour is a rare phenomenon. This report describes such an occurrence in a gastric large cell neuroendocrine carcinoma of a 77-year-old man. The patient presented with dyspepsia, and biopsy of the fungating mass in the cardia showed a high grade neuroendocrine carcinoma. The pre-ope...

journal_title：International journal of surgical pathology

authors： Ip YT,Pong WM,Kao SS,Chan JK

更新日期：2011-06-01 00:00:00

abstract：:To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

journal_title：International journal of surgical pathology

authors： Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

更新日期：2011-04-01 00:00:00

abstract：:Combined lung cancers containing both small cell and non-small cell carcinoma elements are uncommon but well recognized. Lung tumors with neuroendocrine differentiation form a group of histologically distinct tumors with differing clinical behavior ranging from low-grade tumors with good prognosis (typical carcinoid) ...

journal_title：International journal of surgical pathology

authors： Owens CL,Fraire AE

更新日期：2011-04-01 00:00:00

abstract：AIM:To describe a case of metastasis of malignant peritoneal epithelioid mesothelioma in gastric antral mucosa in a patient with a cryptogenic liver cirrhosis associated with esophageal varices, abdominal pain and distension, ascites, and weight loss. MATERIALS AND METHOD:The patient underwent esophageal gastric endos...

journal_title：International journal of surgical pathology

authors： Daniele L,Righi A,Ferraris A,Macrì L,Asioli S

更新日期：2011-04-01 00:00:00

abstract：:Sclerosing cholangitis is an autoimmune condition characterized by lymphocytic infiltration within the biliary epithelium leading to multifocal stricturing of the biliary tree. Primary sclerosing cholangitis (PSC) is the most common type encountered clinically. However, a similar process may occur in conjunction with ...

journal_title：International journal of surgical pathology

authors： Ong SL,Garcea G,Puls F,Richards C,Mulcahy K,Grant A,Dennison AR,Berry DP

更新日期：2011-02-01 00:00:00

abstract：:Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special tec...

journal_title：International journal of surgical pathology

authors： Nistal M,Gonzalez-Peramato P,Serrano A,Reyes-Mugica M,Cajaiba MM

更新日期：2011-02-01 00:00:00

abstract：:Transitional cell tumors of the ovary comprise about 1% to 2% of all ovarian neoplasms. Most of these tumors are benign Brenner tumors and account for about 5% of benign surface epithelial-stromal tumors. Spicules of calcifications are found in the stroma of about 50% of benign Brenner tumors. Although diagnostic chal...

journal_title：International journal of surgical pathology

authors： Vemavarapu L,Alatassi H,Moghadamfalahi M

更新日期：2011-02-01 00:00:00

abstract：:The development of squamous metaplasia or carcinoma is a rare occurrence in the setting of a ruptured or leaking silicone breast implant capsule. However, the oncogenic process in such a context is yet another intriguing example of how chronic inflammation plays an integral role in the tumorigenic process. Recent pape...

journal_title：International journal of surgical pathology

authors： Alikhan MB,Nassar A,Mansoor I

更新日期：2010-12-01 00:00:00

abstract：:Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...

journal_title：International journal of surgical pathology

authors： Di Tommaso L,Rahal D,Bossi P,Roncalli M

更新日期：2010-12-01 00:00:00

abstract：:Goblet cell carcinoid (GCC) of the appendix is characterized by a dual differentiation of both endocrine and gland. This study, therefore, explores its clinicopathological and immunohistochemical features. The authors reviewed clinicopathological and immunohistochemical features of 26 GCC cases in Southwest China betw...

journal_title：International journal of surgical pathology

authors： Yong Jiang,Huawei Liu,Hu Long,Yingying Yang,Dianying Liao,Xiuhui Zhang

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:Renal cell carcinomas (RCCs) in children and adolescents are much rarer than in adults. In this age group, Xp11.2 translocation RCCs were the most common subtype of pediatric RCCs. Information regarding the clinical behavior of pediatric RCCs remains controversial because of their relatively rare incidence. ...

journal_title：International journal of surgical pathology

authors： Qiu Rao,Bing Guan,Zhou XJ

更新日期：2010-12-01 00:00:00

abstract：:A 25-year-old patient presented with epigastric pain, which on gastric biopsy revealed the characteristic appearance of collagenous gastritis. There was a thick prominent subepithelial band that was confirmed to be collagen with a Masson's trichrome stain. There was associated Helicobacter pylori gastritis but no evid...

journal_title：International journal of surgical pathology

authors： Jain R,Chetty R

更新日期：2010-12-01 00:00:00

abstract：:Simple melanosis of the bladder is an uncommon condition with fewer than 15 reported cases characterized by multifocal, diffuse melanin pigmentation of the urothelial mucosa. It is frequently associated with urinary incontinence or urgency. Histologically, melanin granules are present within urothelial cells or lamina...

journal_title：International journal of surgical pathology

authors： Talmon GA,Khan AU,Koerber RK,Johansson SL

更新日期：2010-12-01 00:00:00

abstract：:A 61-year-old woman presented with solitary lymphadenopathy suspicious for lymphoma. An excisional biopsy of a right inguinal lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected, but a primary nasopharyngeal mass was identified. A microscopic examination of the nasopharyngeal ...

journal_title：International journal of surgical pathology

authors： Wu KN,McCue PA,Berger A,Spiegel JR,Wang ZX,Witkiewicz AK

更新日期：2010-10-01 00:00:00

abstract：:Sclerosing spindle cell rhabdomyosarcoma (SSRMS) is a newly recognized entity in adults. The authors report a new case of SSRMS in a 31-year-old woman who presented with a large right leg mass. Biopsy revealed a malignant spindle cell neoplasm with focal sclerotic areas. A diagnosis of monophasic synovial sarcoma was ...

journal_title：International journal of surgical pathology

authors： Gavino AC,Spears MD,Peng Y

更新日期：2010-10-01 00:00:00

abstract：:Enfuvirtide (ENF, T-20, or Fuzeon [Hoffman-La Roche Inc, Nutley, NJ, and Trimeris, Inc, Durham, NC]) is an HIV-1 fusion inhibitor and is the only injectable antiretroviral drug available. Injection site reactions (ISRs) are the most frequently reported adverse events, occurring in about 98% of patients. A granuloma an...

journal_title：International journal of surgical pathology

authors： Sidhu HK,Chaffee BH,Tvetenstrand CD,Sidhu JS

更新日期：2010-10-01 00:00:00

abstract：:Colonic perineurioma has been depicted as characterized by a mucosal proliferation of monomorphic spindle perineurial cells leading to an evident separation, distortion, and entrapment of colonic crypts. The authors, however, believe that a sizable subset of the cases differ in that they display only a limited perineu...

journal_title：International journal of surgical pathology

authors： Groisman G,Amar M,Alona M

更新日期：2010-08-01 00:00:00

abstract：:Because of its rarity, pathologic and clinical features of Hodgkin lymphoma-like posttransplant lymphoproliferative disorder (HL-like PTLD) are not well understood, and it is unclear whether its biological behavior is more closely related to classical Hodgkin disease or to monomorphic B-cell PTLD. The authors compared...

journal_title：International journal of surgical pathology

authors： Krishnamurthy S,Hassan A,Frater JL,Paessler ME,Kreisel FH

更新日期：2010-08-01 00:00:00

abstract：:This study describes the clinical, histologic, and immunohistochemical features of four cases of GI PEComa. The size of the tumors ranged from 3.5 to 6.0cm in diameter, and all were located in wall of the large bowel. Microscopically, the tumors were characterized by an epithelioid arrangement of tumor cells, which ha...

journal_title：International journal of surgical pathology

authors： Shi HY,Wei LX,Sun L,Guo AT

更新日期：2010-08-01 00:00:00

abstract：:In this study, the pathogenesis of clear cell change in colorectal epithelial lesions was studied. A total of 4 cases of clear cell change (1 hyperplasic polyp and 3 adenomas) were characterized using histochemistry, immunohistochemistry, and electron microscopy. All lesions developed in the left colon. In all, 1 aden...

journal_title：International journal of surgical pathology

authors： Eloy C,Lopes JM,Faria G,Moreira H,Brandão A,Silva T,Carneiro F

更新日期：2009-12-01 00:00:00

abstract：:Benign lymphoepithelial cyst (BLC) of the salivary gland is uncommon. Among report of these lesions, there were no previous cases of lymphoepithelial lesion (LeL) in human immunodeficiency virus type-1 (HIV-1) unrelated BLC. This study reports 3 cases of HIV-unrelated BLC containing LeL-like structures. Pathologically...

journal_title：International journal of surgical pathology

authors： Kojima M,Nakamura N,Matsuda H,Kaba S,Itoh H,Masawa N

更新日期：2009-12-01 00:00:00

abstract：:Pleomorphic adenoma with foci of squamous and mucinous differentiation can potentially be misdiagnosed as low-grade mucoepidermoid carcinoma. The circumscribed borders of the tumor, gradual merging of mucoepidermoid foci into areas typical of pleomorphic adenoma, and presence of keratinization are features against the...

journal_title：International journal of surgical pathology

authors： Guo SP,Cheuk W,Chan JK

更新日期：2009-08-01 00:00:00

abstract：:Diverticulosis of the appendix is a relatively rare pathological finding. The majority are acquired pseudodiverticula. True congenital diverticula are very rare. Appendiceal diverticulosis is usually an incidental finding and clinically asymptomatic. When symptomatic, it is usually complicated by acute or chronic dive...

journal_title：International journal of surgical pathology

authors： Abdullgaffar B

更新日期：2009-06-01 00:00:00

abstract：:The aim of this study is to analyze all the cases of benign fibro-osseous lesions treated at School and Hospital of Stomatology, Wuhan University, to compare the results obtained in this study with those previously documented by other authors. The 127 cases diagnosed as a fibro-osseous lesion were retrieved, and infor...

journal_title：International journal of surgical pathology

authors： Alsharif MJ,Sun ZJ,Chen XM,Wang SP,Zhao YF

更新日期：2009-04-01 00:00:00

abstract：:In this report, a case of metaplastic thymoma arising in a thymic cyst wall is discussed. The patient was a 61-year-old male whose chief complaint was sweating and chest pain. Imaging study revealed a mediastinal mass with right hemithoracic extension. He underwent surgical resection of the mass and remnants of the th...

journal_title：International journal of surgical pathology

authors： Poorabdollah M,Mehdizadeh E,Mohammadi F,Sabeti S

更新日期：2009-02-01 00:00:00

abstract：:The majority of alveolar RMSs have t(2;13)(q35;q14) or (1:13)(p36;q14),which generate PAX3/7 -FKHR fusion genes. Here, the authors detected the PAX3/7-FKHR fusion transcripts in 17 formalin-fixed, paraffin-embedded RMSs and 26 other SRCTs using one-step RT-PCR. PAX3 -FKHR and PAX7-FKHR transcripts were positive in 4/8...

journal_title：International journal of surgical pathology

authors： Chang B,Pang LJ,Qi Y,Liu CX,Cao Y,Li HA,Hu WH,Jiang JF,Zhang WJ,Li F

更新日期：2009-02-01 00:00:00

abstract：:The authors describe a case of multifocal perivascular epithelioid cell tumor (PEComa) arising in the pelvis of a 39-year-old woman affected by tuberous sclerosis. The tumor presented in the form of multiple fascicular, focally cystic nodules involving the uterine corpus, both ovaries, and the omentum. Microscopically...

journal_title：International journal of surgical pathology

authors： Froio E,Piana S,Cavazza A,Valli R,Abrate M,Gardini G

更新日期：2008-10-01 00:00:00

abstract：:To elucidate the relationship between del(5q) and the clinical and histological features of small cell neuroendocrine lung carcinoma, 33 tissue samples from patients with this tumor were evaluated. By using fluorescence in situ hybridization, del(5q) was identified in almost 50% of cases (15/33, 45%). Clinically, pati...

journal_title：International journal of surgical pathology

authors： Hartel PH,Shackelford AL,Hartel JV,Wenger SL

更新日期：2008-10-01 00:00:00

abstract：:Fibroadenoma and phyllodes tumors of the breast exhibit a continuum of pathologic features. We examined phyllodes tumors initially called fibroadenoma for features that may accurately classify the tumor as phyllodes tumor on the first biopsy specimen. The phyllodes tumors initially called fibroadenoma for features tha...

journal_title：International journal of surgical pathology

authors： Yohe S,Yeh IT

更新日期：2008-04-01 00:00:00

abstract：:A high level of serum alpha-fetoprotein (AFP) is typically indicative of hepatocellular carcinoma in patients with liver lesions. In this article, we describe an exceptional case of intrahepatic cholangiocarcinoma that occurred in a 36-year-old man with a markedly elevated serum AFP level (12310.7 ng/mL). Histopatholo...

journal_title：International journal of surgical pathology

authors： Vij K,Wang HL

更新日期：2008-04-01 00:00:00

abstract：:Micrometastases in lymph nodes and blood may provide important prognostic information. In this study, cytokeratin 20 (CK20) positive cells in lymph nodes and circulating CK20 mRNA were studied using 57 paraffin-embedded lymph node specimens and blood from 24 patients with pN0 colorectal cancer (CRC), respectively. Res...

journal_title：International journal of surgical pathology

authors： Wong CS,Cheung MT,Ma BB,Pun Hui E,Chan AC,Chan CK,Lee KC,Cheuk W,Lam MY,Wong MC,Chan CM,Chan JK,Chan AT

更新日期：2008-04-01 00:00:00

abstract：:Reduction mammoplasty is a frequently performed procedure for the treatment of macromastia and for the achievement of symmetry in breast cancer patients following lumpectomy. Slides from 516 consecutive bilateral reduction mammoplasties performed for macromastia over 15 years were reviewed. Among these, 92 (18%) low-r...

journal_title：International journal of surgical pathology

authors： Dotto J,Kluk M,Geramizadeh B,Tavassoli FA

更新日期：2008-01-01 00:00:00

abstract：:Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...

journal_title：International journal of surgical pathology

authors： Winarti NW,Argani P,De Marzo AM,Hicks J,Mulyadi K

更新日期：2008-01-01 00:00:00

abstract：:NET-1 is a member of the NET-x family. To explore the potential role of NET-1 in hepatocellular carcinoma (HCC), the expression of NET-1 and the relationship with HCC were examined for the first time. We found that NET-1 was frequently expressed in HCC and the peritumor tissue. The relative amounts of NET-1 mRNA in HC...

journal_title：International journal of surgical pathology

authors： Chen L,Wang Z,Zhan X,Li DC,Zhu YY,Zhu J

更新日期：2007-10-01 00:00:00

abstract：:Synchronous tumors of the stomach are uncommon. We present a unique case of gastric synchronous tumors composed of signet-ring cell adenocarcinoma and gastrointestinal stromal tumor (GIST). The two tumors arose at the same site and were sharply juxtaposed without intermingling of morphologically distinct elements. Coi...

journal_title：International journal of surgical pathology

authors： Lee FY,Jan YJ,Wang J,Yu CC,Wu CC

更新日期：2007-10-01 00:00:00

abstract：:In this study, we examined aberrant methylation of the E-cadherin, estrogen receptor, RB1 , p16, p15, p14, and MGMT genes by the methylation-specific polymerase chain reaction method in 101 gastric carcinomas. Hypermethylation was detected in E-cadherin, estrogen receptor, RB1, p16, p14, p15, and MGMT at the rates of ...

journal_title：International journal of surgical pathology

authors： Zhao YF,Zhang YG,Tian XX,Juan Du,Jie Zheng

更新日期：2007-07-01 00:00:00

abstract：:Gustav Giemsa was born in Germany in 1867, worked mainly as a chemist, and died in 1948. The staining method, which carries his name, was designed primarily for the demonstration of parasites in malaria, but it was also employed in histology because of the high-quality staining of the chromatin and the nuclear membran...

journal_title：International journal of surgical pathology

authors： Barcia JJ

更新日期：2007-07-01 00:00:00

abstract：:Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype...

journal_title：International journal of surgical pathology

authors： Alexiev BA,Alaish SM,Sun CC

更新日期：2007-07-01 00:00:00

abstract：:Rhabdomyosarcoma is an aggressive malignant tumor often developing in the head and neck in children. In the sinonasal region, rhabdomyosarcoma constitutes a clinically important group because of the difficulty of surgical resection and its generally poor prognosis. We reviewed the archival pathology materials of 39 ca...

journal_title：International journal of surgical pathology

authors： Ahmed AA,Tsokos M

更新日期：2007-04-01 00:00:00